Nerve growth factor
Discovery and characterization of nerve growth factor, a protein essential to the growth and survival of certain neurons.
Scientist Exhibit
Biology & Life Sciences • Medicine & Health
Co-discovered nerve growth factor
Overview
Rita Levi-Montalcini investigated how nerve cells grow and survive. Barred from university work under Fascist racial laws, she continued experiments in a small laboratory assembled at home. Her later research with Stanley Cohen led to the identification of nerve growth factor, opening new paths in developmental biology, neuroscience, and medical research.
Scientific Contribution
Discovery and characterization of nerve growth factor, a protein essential to the growth and survival of certain neurons.
Life Timeline
career
Levi-Montalcini was invited to Washington University in St. Louis, where she continued research on nervous-system development.
discovery
Her experiments showed that mouse tumours released a substance that stimulated vigorous nerve growth in chick embryos.
career
Levi-Montalcini and Stanley Cohen began the collaboration that led to the identification and isolation of nerve growth factor.
award
Levi-Montalcini shared the Nobel Prize with Stanley Cohen for their discoveries of growth factors.
Places & Networks
university
St. Louis , United States
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Rome , Italy
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